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Article

Comparative genomics of high grade neuroendocrine carcinoma of the cervix.

PloS one - 1 Jan 2020

Hillman R Tyler, Cardnell Robert, Fujimoto Junya, Lee Won-Chul, Zhang Jianjun, Byers Lauren A, Ramalingam Preetha, Leitao Mario, Swisher Elizabeth, Futreal P Andrew, Frumovitz Michael

Abstract excerpt

In order to improve treatment selection for high grade neuroendocrine carcinomas of the cervix (NECC), we performed a comparative genomic analysis between this rare tumor type and other cervical cancer types, as well as extra-cervical neuroendocrine small cell carcinomas of the lung and bladder. We performed whole exome sequencing on fresh-frozen tissue from 15 NECCs and matched normal tissue. We then identified...

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Identifiers

PMID: 32544169
DOI: 10.1371/journal.pone.0234505
PMCID: PMC7297329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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