Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome Variation in Alcohol Use Disorder by Whole-Exome Sequencing.

Addiction biology - 1 Aug 2025

Liu Lei, Zhang Bo, Dong Yong, Liu Li Ping, Wang Jing Ying, Liu Jun, Zhou Guang Yu, Kang Chuan Yi, Hu Xiaorui, Cheng Chang, Zhao Na, Lu Jia, Wang Huaizhi, Hu Jian, Wang Xiaohong

Abstract excerpt

Alcohol use disorder is closely related to genetic and environmental factors. However, the contribution of coding variation to alcohol use disorder susceptibility remains poorly understood. We aimed to identify genetic mutations in alcohol use disorder by whole exon sequencing. We performed whole-exome sequencing in 83 patients with alcohol use disorder and compared it with exome sequences of healthy controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Polymorphism, Single Nucleotide
Share to Alcoholism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Exome Sequencing

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to INDEL Mutation

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 40730494
DOI: 10.1111/adb.70070
PMCID: PMC12307094

Genes

CCHCR1
CNTNAP3
ESRRA
ZNF45
ZNF683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome Variation in Alcohol Use Disorder by Whole-Exome Sequencing.PMID 40730494Read ↗

Whole exome sequencing analysis identifies genes for alcohol consumption.Semantic proximity Read ↗

Investigating the Contribution of Coding Variants in Alcohol Use Disorder Using Whole-Exome Sequencing Across Ancestries.Semantic proximity Read ↗

Investigation of Association of Rare, Functional Genetic Variants With Heavy Drinking and Problem Drinking in Exome Sequenced UK Biobank Participants.Semantic proximity Read ↗

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholismSemantic proximity Read ↗

Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.Semantic proximity Read ↗

Human genetics and epigenetics of alcohol use disorder.Semantic proximity Read ↗

Genetic variation in the exome: Associations with alcohol and tobacco co-use.Semantic proximity Read ↗

The GENCODE exome: sequencing the complete human exome.Semantic proximity Read ↗

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117)Semantic proximity Read ↗

Genome-wide association discoveries of alcohol dependenceSemantic proximity Read ↗

Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Semantic proximity Read ↗

Genome-wide meta-analysis of copy number variations with alcohol dependence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.