Article
Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.
Alcoholism, clinical and experimental research - 1 Aug 2015
Clark Shaunna L, Aberg Karolina A, Nerella Srilaxmi, Kumar Gaurav, McClay Joseph L, Chen Wenan, Xie Linying Y, Harada Aki, Shabalin Andrey A, Gao Guimin, Bergen Sarah E, Hultman Christina M, Magnusson Patrik K E, Sullivan Patrick F, van den Oord Edwin J C G
Abstract excerpt
BACKGROUND: Methylome-wide association (MWAS) studies present a new way to advance the search for biological correlates for alcohol use. A challenge with methylation studies of alcohol involves the causal direction of significant methylation-alcohol associations. One way to address this issue is to combine MWAS data with genomewide association study (GWAS) data. METHODS: Here, we combined MWAS and GWAS results...
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