Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of Association of Rare, Functional Genetic Variants With Heavy Drinking and Problem Drinking in Exome Sequenced UK Biobank Participants.

Alcohol and alcoholism (Oxford, Oxfordshire) - 9 Jul 2022

Curtis David

Abstract excerpt

AIMS: The study aimed to identify specific genes and functional genetic variants affecting susceptibility to two alcohol-related phenotypes: heavy drinking and problem drinking. METHODS: Phenotypic and exome sequence data were downloaded from the UK Biobank. Reported drinks in the last 24 hours were used to define heavy drinking, while responses to a mental health questionnaire defined problem drinking. Gene-wise...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Dehydrogenase
Share to Alcohol Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alcoholism

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Biological Specimen Banks

Share to Forkhead Transcription Factors

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 33893496
DOI: 10.1093/alcalc/agab031
PMCID: PMC9270990

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of Association of Rare, Functional Genetic Variants With Heavy Drinking and Problem Drinking in Exome Sequenced UK Biobank Participants.PMID 33893496Read ↗

Whole exome sequencing analysis identifies genes for alcohol consumption.Semantic proximity Read ↗

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).Semantic proximity Read ↗

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117)Semantic proximity Read ↗

Investigating the Contribution of Coding Variants in Alcohol Use Disorder Using Whole-Exome Sequencing Across Ancestries.Semantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption in the UK Biobank: A Mendelian Randomisation Study.Semantic proximity Read ↗

A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals.Semantic proximity Read ↗

A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Semantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption: A Mendelian Randomisation StudySemantic proximity Read ↗

Genomic influences on alcohol problems in a population-based sample of young adults.Semantic proximity Read ↗

Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia.Semantic proximity Read ↗

Genome Variation in Alcohol Use Disorder by Whole-Exome Sequencing.Semantic proximity Read ↗

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.