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Article

Evaluating the Longitudinal Association of Rheumatoid Arthritis Disease Activity With Phenotypic Frailty: Evidence for Secondary Frailty?

Arthritis care & research - 1 Mar 2026

Brubeck Hannah F, Riggles Kylie E, Bass Riley S, Wahl Elizabeth R, Mount George, Shoback Dolores M, Andrews James S, Garcia Jose M, Orkaby Ariela R, Baker Joshua F, Katz Patricia P, Wysham Katherine D, Loecker Courtney N

Abstract excerpt

OBJECTIVE: The cross-sectional association between rheumatoid arthritis (RA) disease activity and frailty has been described; however, the longitudinal relationship is less well understood. We evaluated the association between disease activity and frailty over time. METHODS: We used a longitudinal RA cohort established at the Department of Veterans Affairs Puget Sound Health Care System. RA disease activity...

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PMID: 40702741
DOI: 10.1002/acr.25615
PMCID: PMC12747155

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