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Article

Development and validation of a frailty index for use in the osteoarthritis initiative.

Age and ageing - 1 Jun 2024

O'Brien Myles W, Maxwell Selena P, Moyer Rebecca, Rockwood Kenneth, Theou Olga

Abstract excerpt

BACKGROUND: The Osteoarthritis Initiative (OAI) evaluates the development and progression of osteoarthritis. Frailty captures the heterogeneity in aging. Use of this resource-intensive dataset to answer aging-related research questions could be enhanced by a frailty measure. OBJECTIVE: To: (i) develop a deficit accumulation frailty index (FI) for the OAI; (ii) examine its relationship with age and compare between...

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Identifiers

PMID: 38935532
DOI: 10.1093/ageing/afae125
PMCID: PMC11210396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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