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Article

Association of phenotypic frailty and hand grip strength with telomere length in SLE.

Lupus science & medicine - 22 Mar 2024

Lieber Sarah B, Lipschultz Robyn A, Syed Shahrez, Rajan Mangala, Venkatraman Sara, Lin Myriam, Reid M Carrington, Lue Neal F, Mandl Lisa A

Abstract excerpt

OBJECTIVE: Frailty and objective hand grip strength (one of the components of the frailty phenotype) are both risk factors for worse health outcomes in SLE. Whether telomere length, an established cellular senescence marker, is a biologic correlate of the frailty phenotype and hand grip strength in patients with SLE is not clear. First, we aimed to evaluate differences in telomere length between frail and...

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Identifiers

PMID: 38519061
DOI: 10.1136/lupus-2023-001008
PMCID: PMC10961526

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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