Article
Fibroblast Growth Factor-23 and Frailty in Elderly Community-Dwelling Individuals: The Cardiovascular Health Study.
Journal of the American Geriatrics Society - 1 Feb 2016
Beben Tomasz, Ix Joachim H, Shlipak Michael G, Sarnak Mark J, Fried Linda F, Hoofnagle Andrew N, Chonchol Michel, Kestenbaum Bryan R, de Boer Ian H, Rifkin Dena E
Abstract excerpt
OBJECTIVES: To evaluate whether fibroblast growth factor 23 (FGF-23) is related to frailty and to characterize the nature of their joint association with mortality. DESIGN: Cross-sectional analysis for frailty and longitudinal cohort analysis for mortality. SETTING: Cardiovascular Health Study. PARTICIPANTS: Community-dwelling individuals (N = 2,977; mean age 77.9 ± 4.7, 40% male, 83% white). MEASUREMENTS: The...
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