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Article

Frailty phenotype as mediator between systemic inflammation and osteoporosis and fracture risks: A prospective study.

Journal of cachexia, sarcopenia and muscle - 1 Jun 2024

Di Dongsheng, Zhou Haolong, Cui Zhangbo, Zhang Jianli, Liu Qian, Yuan Tingting, Zhou Tingting, Luo Xiao, Ling Danyang, Wang Qi

Abstract excerpt

BACKGROUND: Systemic inflammation and frailty have been implicated in osteoporosis (OP) and fracture risks; however, existing evidence remains limited and inconclusive. This study aimed to assess the associations of systemic inflammation and frailty phenotype with incident OP and fracture and to evaluate the mediating role of frailty phenotype. METHODS: The present study analysed data from the UK Biobank, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38468152
DOI: 10.1002/jcsm.13447
PMCID: PMC11154788

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