Article
Individualized Mini-Panel Sequencing of ctDNA Allows Tumor Monitoring in Complex Karyotype Sarcomas.
International journal of molecular sciences - 6 Sept 2022
Braig David, Runkel Alexander, Eisenhardt Anja E, Schmid Adrian, Zeller Johannes, Pauli Thomas, Lausch Ute, Wehrle Julius, Bronsert Peter, Jung Matthias, Kiefer Jurij, Boerries Melanie, Eisenhardt Steffen U
Abstract excerpt
Soft tissue sarcomas (STS) are rare tumors of mesenchymal origin with high mortality. After curative resection, about one third of patients suffer from distant metastases. Tumor follow-up only covers a portion of recurrences and is associated with high cost and radiation burden. For metastasized STS, only limited inferences can be drawn from imaging data regarding therapy response. To date there are no...
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