Causal Relationship Between Matrix Metalloproteinase with Their Tissue Inhibitors and Human Immunodeficiency Virus Infection: A Two-Sample Bidirectional Mendelian Randomization Analysis.

Abstract excerpt

Studies have shown an association between matrix metalloproteinases (MMPs) along with tissue inhibitors of MMPs (TIMP) and human immunodeficiency virus (HIV) infection and CD4+ T cell count, a key clinical indicator for HIV progression, but the causality remains unclear. This study aimed to investigate the bidirectional causal relationship between MMPs/TIMP and HIV. A genome-wide association study-based...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CD4 Lymphocyte Count
• Share to CD4 gene