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Causal relationships between gut microbiota, plasma metabolites, and HIV infection: insights from Mendelian randomization and mediation analysis

30 Aug 2024

Abstract excerpt

OBJECTIVE: Gut dysbiosis and metabolic abnormalities have been implicated in HIV infection. However, the exact causal relationships among the gut microbiota, metabolites, and HIV infection remain poorly understood. Our study involving Mendelian randomization (MR) and mediation analysis aims to unveil these causalities. METHODS: Genetic instrumental variables for the gut microbiota were retrieved from MiBioGen...

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Share to Epigenetics and DNA Methylation
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PMID: 39215321
DOI: 10.1186/s12985-024-02480-1

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