Article
Associations between genetically predicted TIMP-3 levels and risk of venous thromboembolism: A two sample Mendelian randomization study.
Journal of pharmaceutical and biomedical analysis - 15 Sept 2024
Li Yang, Wang Xiaoyu, Zhang Xiangyu, Chen Qianqian, Shi Xiaowen, Zhang Bin, Xu Jianjiang, Han Bingjiang
Abstract excerpt
TIMP metallopeptidase inhibitor 3 (TIMP-3) may contribute to the pathogenesis of venous thromboembolism (VTE). However, few studies have investigated the effect of TIMP-3 on VTE. Therefore, a two-sample Mendelian randomization (MR) analysis was conducted to investigate the association between TIMP-3 levels and VTE. Seven independent single-nucleotide polymorphisms (SNPs) for TIMP-3 levels were obtained from a...
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