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Molecular insights into glioblastoma progression: role of CHCHD2P9 in tumor heterogeneity and prognosis

24 Jun 2025

Abstract excerpt

Background: Gliomas are highly aggressive, life-threatening tumors with poor prognosis, and remain a leading cause of mortality among brain cancers. Although the role of mitochondrial proteins in cancer has garnered increasing attention, their specific functions in the nervous system, particularly in gliomas, remain poorly understood. Methods: We integrated single-cell RNA sequencing with cellular assays and flow...

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PMID: 40630954
DOI: 10.3389/fimmu.2025.1581850

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