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Comparative Analysis of the Tumour Mutational Burden in Erosive and Reticular Oral Lichen Planus.

Oral diseases - 1 Dec 2025

Leão Priscila Laiza Rubim, Moreira Rennan Garcias, Rocha Fernanda Faria, de Freitas Xavier Laura, Martins-Chaves Larissa Rany, de Oliveira Ana Carolina Carneiro Batista, Almeida Soraya de Mattos Camargo Grossmann, de Sousa Silvia Ferreira, Diniz Marina Gonçalvez, Martins-Chaves Roberta Rayra, Gomez Ricardo Santiago

Abstract excerpt

OBJECTIVE: Oral lichen planus (OLP) is a chronic inflammatory disease classified as an oral potentially malignant lesion. The erosive and reticular forms of OLP have the potential for malignant transformation, with no consistent data indicating that one form is more likely to undergo malignant transformation than the other. Tumour mutational burden (TMB) is a parameter that represents the number of somatic...

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Identifiers

PMID: 40616231
DOI: 10.1111/odi.70020
PMCID: PMC12989049

Genes

ATRX
BRCA2
CD274
PALB2
PSMA6
PTPRD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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