Article
Genome-wide characterization of the mutational landscape of proliferative verrucous leukoplakia.
Oral surgery, oral medicine, oral pathology and oral radiology - 1 Jul 2024
Farah Camile S, Shearston Kate, Melton Phillip E, Fox Simon A
Abstract excerpt
OBJECTIVES: Proliferative verrucous leukoplakia (PVL) is a rare but highly aggressive variant of oral leukoplakia that almost inevitably progresses to oral squamous cell carcinoma (OSCC). The aims of this study were to perform whole exome sequencing of a cohort of patients diagnosed with PVL and identify potential mutational profiles and pathways in this disorder. STUDY DESIGN: A total of 12 oral cavity mucosal...
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