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Bidirectional Mendelian Randomization Study: Unraveling the Link Between Idiopathic Pulmonary Fibrosis and Cardiovascular Disease.

Annals of human genetics - 1 Jan 2026

Hu Lijuan, Liu Ruoyu, Yang Liang, Xu Mingyuan, Zhou Yun, Cao Yongtong

Abstract excerpt

BACKGROUND: Idiopathic pulmonary fibrosis (IPF), the predominant idiopathic interstitial pneumonia, is marked by progressive, irreversible lung damage with a 3-year median survival rate in the elderly. Cardiovascular disease (CVD) is the most common disease in the elderly population and its incidence is increasing all the time, especially in the Asia-Pacific region, coinciding with the rise in global mortality....

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PMID: 40613241
DOI: 10.1111/ahg.12605

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