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Two-sample Mendelian randomization analysis unveils a potential genetic association between rheumatic diseases and the risk of idiopathic pulmonary fibrosis.

Medicine - 22 May 2026

Tan Wei, Ding Jurong, Wang Jingjing, Wang Shanmei

Abstract excerpt

This study aims to elucidate the genetically causal link between rheumatic diseases and idiopathic pulmonary fibrosis (IPF) using Mendelian randomization (MR) analysis. Genome-wide association studies data for IPF were sourced from the FINN cohort in the IEU database, rheumatoid arthritis (RA), systemic lupus erythematosus data, and Sjögren syndrome data from the European Bioinformatics Institute, and ankylosing...

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Arthritis, Rheumatoid
Genome-Wide Association Study
Idiopathic Pulmonary Fibrosis
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rheumatic Diseases

Sjogren's Syndrome

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Identifiers

PMID: 42175437
DOI: 10.1097/MD.0000000000048543
PMCID: PMC13200970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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