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Article

Causal association between rheumatoid arthritis and interstitial lung disease: A two-sample bidirectional Mendelian randomization study.

Medicine - 20 Feb 2026

Peng Jinxiang, Chen Haozhu, Tan Jinmei, Chen Zhuang, Wu Feng

Abstract excerpt

Epidemiological observations suggest a potential causal relationship between rheumatoid arthritis (RA) and interstitial lung disease (ILD), and vice versa. Alternatively, this association could be due to simple co-occurrence of RA and ILD resulting from shared population genetic or environmental risk factors. However, the causal nature of this relationship remains uncertain. This study aims to investigate the...

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Share to Arthritis, Rheumatoid
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Lung Diseases, Interstitial

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

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Identifiers

PMID: 41731788
DOI: 10.1097/MD.0000000000047542
PMCID: PMC12928876

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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