Article
Causal Association Between Idiopathic Pulmonary Fibrosis and Coronary Artery Disease: A Bidirectional Two-Sample Mendelian Randomization.
British journal of hospital medicine (London, England : 2005) - 23 Jul 2026
Yang Lirui, Zhao Xin, Feng Tingting, Li Jiang
Abstract excerpt
AIMS/BACKGROUND: Coronary artery disease (CAD) has been epidemiologically linked to idiopathic pulmonary fibrosis (IPF); however, the genetic basis of this association remains unclear. Therefore, this study aims to investigate the potential causal relationships between IPF and CAD using a bidirectional two-sample Mendelian randomization (MR) strategy. METHODS: Inverse-variance weighted (IVW), MR-Egger, weighted...
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