Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring bone-tumor interactions through 3D in vitro models: Implications for primary and metastatic cancers

17 Jun 2025

Abstract excerpt

Bone tissue serves as a perfect hosting site where metastatic cancer cells of the most prevalent cancer types, such as prostate and breast cancers, as well as the native bone sarcomas, can further proliferate, advancing the disease stage with the consequential decline of the patient’s prognosis. Understanding how the bone niche interacts with tumor cells and the mechanisms leading to drug resistance is a crucial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and treatments
Share to Bone Tissue Engineering Materials
Share to Orthopaedic implants and arthroplasty

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40606222
DOI: 10.1016/j.jbo.2025.100698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring bone-tumor interactions through 3D in vitro models: Implications for primary and metastatic cancersPMID 40606222Read ↗

Bone Endosteal Mimics Regulates Breast Cancer Development and Phenotype.Semantic proximity Read ↗

A 3D-printed scaffold-based osteosarcoma model allows to investigate tumor phenotypes and pathogenesis in an in vitro bone-mimicking nicheSemantic proximity Read ↗

Ex vivo replication of phenotypic functions of osteocytes through biomimetic 3D bone tissue construction.Semantic proximity Read ↗

Tumor microenvironment complexity and therapeutic implications at a glanceSemantic proximity Read ↗

Dual-Lineage Human 3D Bone Niche Model Reveals Osteoclast-Driven Osteomimicry in Prostate CancerSemantic proximity Read ↗

Recapitulating Tumorigenesis in vitro: Opportunities and Challenges of 3D BioprintingSemantic proximity Read ↗

3D In Vitro Model (R)evolution: Unveiling Tumor–Stroma InteractionsSemantic proximity Read ↗

In Vitro Modeling of Non-Solid Tumors: How Far Can Tissue Engineering Go?Semantic proximity Read ↗

Engineered Culture Models for Studies of Tumor-Microenvironment InteractionsSemantic proximity Read ↗

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironmentSemantic proximity Read ↗

Bioengineered human bone-mimetic niche compositions regulate breast cancer cell quiescence and therapy responseSemantic proximity Read ↗

3D geometry orchestrates the transcriptional landscape of metastatic neuroblastoma cells in a multicellular in vitro bone modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.