Article
In Vitro Modeling of Non-Solid Tumors: How Far Can Tissue Engineering Go?
11 Aug 2020
Abstract excerpt
In hematological malignancies, leukemias or myelomas, malignant cells present bone marrow (BM) homing, in which the niche contributes to tumor development and drug resistance. BM architecture, cellular and molecular composition and interactions define differential microenvironments that govern cell fate under physiological and pathological conditions and serve as a reference for the native biological landscape to...
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