Article
3D In Vitro Model (R)evolution: Unveiling Tumor–Stroma Interactions
18 Nov 2020
Abstract excerpt
The complex microenvironment in which malignant tumor cells grow is crucial for cancer progression. The physical and biochemical characteristics of this niche are involved in controlling cancer cell differentiation, proliferation, invasion, and metastasis. It is therefore essential to understand how cancer cells interact and communicate with their surrounding tissue - the so-called tumor stroma - and how this...
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