Article
Importance of Clinical, Laboratory, and Genetic Risk Factors for Incident CAD.
Circulation. Genomic and precision medicine - 1 Aug 2025
Bhattacharya Romit, Marnell Christopher S, Cho So Mi Jemma, Patel Aniruddh P, Ruan Yunfeng, Koyama Satoshi, Jowell Amanda R, Trinder Mark, Haidermota Sara, Lannery Kim, Honigberg Michael C, Zekevat Seyedeh M, Surakka Ida, Peloso Gina M, Natarajan Pradeep
Abstract excerpt
BACKGROUND: Prior work suggests modifiable cardiovascular risk factors (CRFs) account for 80% to 90% of the risk for incident myocardial infarction. The contributions of genetic and other novel CRFs have not been simultaneously assessed in contemporary data sets. METHODS: In the United Kingdom Biobank, CRFs were identified and Cox proportional hazards models with traditional CRFs (hypertension, diabetes,...
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