Article
Joint and interactive associations of body mass index and genetic factors with cardiovascular disease: a prospective study in UK Biobank.
BMC public health - 2 Sept 2024
Huang Ruyu, Kong Xinxin, Geng Rui, Wu Jingwei, Chen Tao, Li Jiong, Li Chunjian, Wu Yaqian, You Dongfang, Zhao Yang, Zhong Zihang, Ni Senmiao, Bai Jianling
Abstract excerpt
BACKGROUND: Both body mass index (BMI) and genetic factors independently contribute to cardiovascular disease (CVD). However, it is unclear whether genetic risk modifies the association between BMI and the risk of incident CVD. This study aimed to investigate whether BMI categories and genetic risk jointly and interactively contribute to incident CVD events, including hypertension (HTN), atrial fibrillation (AF),...
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