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Article

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

2 Jul 2025

Abstract excerpt

Ferroptosis has become a new way to induce cell death in cancer therapy. Deubiquitinating enzymes (DUBs) contribute to cancer ferroptosis, but underlying mechanisms are not completely understood. Here, it is discovered that USP10 as a member of DUBs, is tightly associated with a poor prognosis in patients with head and neck squamous cell carcinoma (HNSCC). Functionally, USP10 inhibits ferroptosis via...

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PMID: 40605431
DOI: 10.1002/advs.202412271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell CarcinomaPMID 40605431Read ↗

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