Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4

17 Jan 2024

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignant tumors, and the mechanisms underlying the anti-ferroptosis of esophageal cancer cells are still largely unclear. This study aims to explore the roles of amplified protein kinase C iota (PKCiota) in the ferroptosis of ESCC cells. Cell viability, colony formation, MDA assay, Western blotting, co-IP, PLA, and RNA-seq technologies are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38247539
DOI: 10.3390/antiox13010114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4PMID 38247539Read ↗

Ferroptosis-related gene AKR1C1 predicts the prognosis of non-small cell lung cancerSemantic proximity Read ↗

Downregulation of ALDH5A1 suppresses cisplatin resistance in esophageal squamous cell carcinoma by regulating ferroptosis signaling pathwaysSemantic proximity Read ↗

Silencing CK19 regulates ferroptosis by affecting the expression of GPX4 and ACSL4 in oral squamous cell carcinoma in vivo and in vitroSemantic proximity Read ↗

Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesisSemantic proximity Read ↗

Ferroptosis-related gene ATG5 is a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinomaSemantic proximity Read ↗

RNF128 promotes gastric cancer progression by inhibiting autophagy-dependent ferroptosis through Beclin1 ubiquitinationSemantic proximity Read ↗

Roles for Autophagy in Esophageal Carcinogenesis: Implications for Improving Patient OutcomesSemantic proximity Read ↗

PRMT4 Reduced Erastin-Induced Ferroptosis in Nasopharyngeal Carcinoma Cisplatin-Resistant Cells by Nrf2/GPX4 PathwaySemantic proximity Read ↗

Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistanceSemantic proximity Read ↗

KLF11 regulates lung adenocarcinoma ferroptosis and chemosensitivity by suppressing GPX4Semantic proximity Read ↗

Transgelin promotes ferroptosis to inhibit the malignant progression of esophageal squamous cell carcinomaSemantic proximity Read ↗

USP2 reversed cisplatin resistance through p53-mediated ferroptosis in NSCLCSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.