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Single-cell RNA sequencing of peripheral blood mononuclear cells reveals complex cellular signalling signatures of metformin treatment type 2 diabetes mellitus

2024-01-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Type 2 diabetes mellitus (T2DM) is a complex polygenic disease. The onset of the disease is related to autoimmunity. However, how immune cells function in the peripheral blood remains to be elucidated. Metformin is the first-line treatment. Exploring biomarkers of T2DM based on single-cell sequencing technology can provide new insights for the discovery of metformin treatment...

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Literature Corpus work
a8f9d854-be9b-5084-ab20-d8fc46454128
DOI
10.1101/2024.01.04.574155
Open publication

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Single-cell RNA sequencing of peripheral blood mononuclear cells reveals complex cellular signalling signatures of metformin treatment type 2 diabetes mellitusDOI 10.1101/2024.01.04.574155
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