Article

Insights into Pathophysiological Pathways in ME/CFS Through Genetic Correlation and Mendelian Randomization

2026-04-10

Abstract excerpt

<title>Abstract</title> <p>Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-acute infection syndromes (PAIS) are multisystem disorders involving immune, vascular, neuroinflammatory, and metabolic abnormalities, yet the causal relevance of these processes remains unclear. Using genome-wide summary statistics from DecodeME (15,579 cases), we performed genetic correlation, pleiotropic heritabilit...

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Literature Corpus work: 4929db1c-7bfd-5f8d-8105-7923c47b7cf7
DOI: 10.21203/rs.3.rs-9363637/v1

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