Article
Identification of candidate genes for endometrial cancer in multi-omics: a Mendelian randomization analysis.
Systems biology in reproductive medicine - 1 Dec 2024
Qin Lan-Hui, Yang Chongze, Song Rui, Chen Pei-Yin, Jiang Zijian, Xu Weihui, Zeng Guanzhen, Liao Jin-Yuan, Long Liling
Abstract excerpt
Endometrial cancer is the most common malignant tumor of the uterus, but the underlying genetic mechanisms of EC remain unclear. To identify candidate genes and investigate genetic mechanisms for endometrial cancer, we utilized the summary-data-based Mendelian randomization (SMR) method to investigate causal associations between genetic variants, gene expression, DNA methylation, and endometrial cancer. Three...
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