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Exploring the shared genetic architecture of type 2 diabetes mellitus and bone mineral density.

Archives of osteoporosis - 23 Jun 2025

Feng Xinran, Xu Hongbin, Guo Qian, Wang Zeying, Ba Ruikai, Xuan Kun, Ban Jinghao

Abstract excerpt

There is a link between type 2 diabetes mellitus (T2DM) and bone mineral density (BMD), but the genetic reasons behind it are not yet clear. Our study found shared genetic markers and key genes connecting T2DM and BMD. This finding helps us understand their co-occurrence and may lead to new therapeutic strategies. PURPOSE: To explore the genetic correlation, causal relationships, and shared risk loci with...

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Share to Bone Density
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 40549202
DOI: 10.1007/s11657-025-01568-7

Genes

BTBD16
CENPW
RNF146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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