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Article

Association of type 2 Diabetes Mellitus and bone mineral density: a two-sample Mendelian randomization study.

BMC musculoskeletal disorders - 12 Feb 2024

Guan Jianbin, Liu Tao, Chen Hao, Yang Kaitan

Abstract excerpt

BACKGROUND: Observational studies have suggested that type 2 Diabetes Mellitus (DM2) is a potentially modifiable risk factor for lower BMD, but the causal relationship is unclear. This study aimed to examine whether the association of DM2 with lower BMD levels was causal by using Mendelian randomization (MR) analyses. METHODS: We collected genome-wide association study data for DM2 and BMD of total body and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38347501
DOI: 10.1186/s12891-024-07195-6
PMCID: PMC10860277

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