Article
Next-generation sequencing of oncogenes and tumor suppressor genes in odontogenic myxomas.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Nov 2017
Santos Jean Nunes, Sousa Neto Ernesto Santos, França Josiane Alves, Diniz Marina Gonçalves, Moreira Rennan Garcias, Castro Wagner Henriques, Gomez Ricardo Santiago, de Sousa Silvia Ferreira, Gomes Carolina Cavalieri
Abstract excerpt
BACKGROUND: Mutations previously considered drivers of malignant neoplasms also occur in benign tumors. From the biological perspective, the study of malignant and benign neoplasms is equally relevant. The study of rare tumors contributes to the understanding of the more common ones, as both could share the same hallmark genetic drivers. The identification of driver mutations in benign tumors is facilitated by...
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