Article
Ring Chromosomes in Patients with Myeloid Neoplasms Are Associated with a Poor Response to Therapy.
Acta haematologica - 1 Jan 2026
Nathan Daniel I, Hoffman Ronald, Ahire Daiva, Mascarenhas John, Marcellino Bridget K, Tremblay Douglas, Silverman Lewis R, Najfeld Vesna, Feld Jonathan
Abstract excerpt
<p>Introduction: Ring chromosomes (RCs) are acquired circular structural abnormalities associated with gain or loss of genetic material, which are thought to be associated with inferior outcomes in patients with myeloid neoplasms (MNs). Responses of patients with MN and RC to the standard therapeutic options have not been previously reported. METHODS: We analyzed the demographics and outcomes of 31 consecutive...
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