Article
Myeloproliferative Neoplasms: Contemporary Review and Molecular Landscape.
International journal of molecular sciences - 12 Dec 2023
Mahmud Muftah, Vasireddy Swati, Gowin Krisstina, Amaraneni Akshay
Abstract excerpt
Myelofibrosis (MF), Myeloproliferative neoplasms (MPNs), and MDS/MPN overlap syndromes have a broad range of clinical presentations and molecular abnormalities, making their diagnosis and classification complex. This paper reviews molecular aberration, epigenetic modifications, chromosomal anomalies, and their interactions with cellular and other immune mechanisms in the manifestations of these disease spectra,...
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