Article
Ring chromosome in myeloid neoplasms is associated with complex karyotype and disease progression.
Human pathology - 1 Oct 2017
Rosenbaum Matthew W, Pozdnyakova Olga, Geyer Julia T, Dal Cin Paola, Hasserjian Robert P
Abstract excerpt
Ring chromosome (RC) is a poorly understood genetic anomaly seen in myeloid neoplasms. This study aims to shed light on the clinical significance of this finding. We identified 96 cases of myeloid neoplasms with RC from 3 academic hospitals. Clinicopathologic features and overall (OS) and leukemia-free survival were reviewed and compared to cases of myeloid neoplasms lacking RC. We identified 59 acute myeloid...
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