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Article

Causal relationships between micronutrients and sarcopenia: a two-sample bidirectional Mendelian randomization study.

Archives of gerontology and geriatrics - 1 Oct 2025

Liu Huilin, Chen Jiahui, Ni Shihao, Long Wenjie, Dong Xiaoming, Liao Huili, Lu Lu, Yang Zhongqi

Abstract excerpt

Sarcopenia, a geriatric syndrome in older adults, significantly impacts quality of life and elevates health risks. This study examines the causal relationships between specific micronutrients-magnesium, selenium, calcium, zinc, iron, phosphorus, and omega-3 fatty acids-and sarcopenia-related traits (SP-traits) using Mendelian randomization (MR) based on genome-wide association studies (GWAS). A bidirectional...

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PMID: 40483991
DOI: 10.1016/j.archger.2025.105917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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