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Article

Causal associations of circulating C-reactive protein with sarcopenia-related traits: A 2-sample Mendelian randomization study.

Medicine - 12 Jun 2026

Li Ji-Ang, Zhou Chen-Han, Liu Ze, Guo Hong-Bin, Liang Jie-Yu, Zhang Yi

Abstract excerpt

This study aimed to evaluate the causal effect of C-reactive protein (CRP) on sarcopenia-related traits (grip strength and appendicular lean mass) utilizing a 2-sample Mendelian randomization (MR) approach. Instrumental variables were sourced from publicly accessible genome-wide association study datasets. To verify the heterogeneity and pleiotropy of the identified instrumental variables, the leave-one-out...

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PMID: 42299584
DOI: 10.1097/MD.0000000000049271

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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