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Sarcopenia, unhealthy lifestyle, and vitamin D: A Mendelian randomization study.

Medicine - 14 Aug 2026

Zhou Xuan, Li Biao, Han Zihui, Ge Hengchao, Wang Quanpeng, Zhang Zhenyong, Zhu Ya, Xu Bin, Wang Xue, Zhu Chengxiu, Zhuang Ruijuan

Abstract excerpt

Observational studies have associated vitamin D deficiency with sarcopenia and lifestyle; however, the causal link between them remains unclear. This study aimed to evaluate the causal relationship between 25-hydroxyvitamin D (25(OH)D) and sarcopenia and unhealthy lifestyle using Mendelian randomization (MR). We extracted pooled data on 25(OH)D from a genome-wide association study conducted on individuals of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42601713
DOI: 10.1097/MD.0000000000050100
PMCID: PMC13480702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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