Article
Causal associations of plasma omega-3 polyunsaturated fatty acids with sarcopenia-related traits: a two-sample Mendelian randomization study.
European journal of clinical nutrition - 1 Jan 2024
Jin Ting, Wang Mengqiao, Zeng Zhen, He Wenming, Zhang Lina, Mai Yifeng, Cen Han
Abstract excerpt
OBJECTIVE: To evaluate the causal effect of plasma omega-3 polyunsaturated fatty acids (PUFAs) on sarcopenia-related traits (lean mass, grip strength and walking pace) utilizing two-sample Mendelian randomization (MR) approach. METHODS: Based on genome-wide association study (GWAS) summary statistics, we performed two-sample MR applying the inverse variance weighted (IVW) as the primary method, supplemented with...
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