Genetically predicted plasma levels of amino acids and stroke risk: a Mendelian randomization study.

Abstract excerpt

Stroke, including ischemic stroke (IS) and small vessel stroke (SVS), is a major cause of morbidity and mortality globally. The role of amino acids remains underexplored in the risk and outcomes of stroke. In the present study, the causal effects of genetically determined amino acid levels on stroke and its functional outcomes were investigated using Mendelian randomization (MR). Data was analyzed by single...

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• Amino Acids
• Genetic Predisposition to Disease
• Ischemic Stroke
• Mendelian Randomization Analysis
• Polymorphism, Single Nucleotide