Article
Causal relationships of circulating amino acids with cardiovascular disease: a trans-ancestry Mendelian randomization analysis.
Journal of translational medicine - 7 Oct 2023
Hu Song, Lin Zhennan, Hu Meng-Jin, Tan Jiang-Shan, Guo Ting-Ting, Huang Xin, Hua Lu
Abstract excerpt
BACKGROUND: Epidemiological studies demonstrated that multiple amino acids (AAs) were associated with cardiovascular diseases (CVDs), but whether these associations were causal remains unclear. This study aims to investigate the causal relationships between circulating levels of 20 AAs and 10 CVDs in European and East Asian populations by Mendelian randomization (MR). METHODS: This MR study utilized...
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