Article
The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study.
BMC medicine - 28 Oct 2022
Lin Chenhao, Sun Zhonghan, Mei Zhendong, Zeng Hailuan, Zhao Manying, Hu Jianying, Xia Mingfeng, Huang Tao, Wang Chaolong, Gao Xin, Zheng Yan
Abstract excerpt
BACKGROUND: Circulating levels of amino acids were associated with blood pressure (BP) in observational studies. However, the causation of such associations has been hypothesized but is difficult to prove in human studies. Here, we aimed to use two-sample Mendelian randomization analyses to evaluate the potential causal associations of circulating levels of amino acids with BP and risk of hypertension. METHODS:...
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