Article
State of Art of Cancer Pharmacogenomics in Latin American Populations.
International journal of molecular sciences - 23 May 2017
López-Cortés Andrés, Guerrero Santiago, Redal María Ana, Alvarado Angel Tito, Quiñones Luis Abel
Abstract excerpt
Over the past decades, several studies have shown that tumor-related somatic and germline alterations predicts tumor prognosis, drug response and toxicity. Latin American populations present a vast geno-phenotypic diversity due to the great interethnic and interracial mixing. This genetic flow leads to the appearance of complex characteristics that allow individuals to adapt to endemic environments, such as high...
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