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Cancer Genomics: Diversity and Disparity Across Ethnicity and Geography

18 Nov 2015

Abstract excerpt

Ethnic and geographic differences in cancer incidence, prognosis, and treatment outcomes can be attributed to diversity in the inherited (germline) and somatic genome. Although international large-scale sequencing efforts are beginning to unravel the genomic underpinnings of cancer traits, much remains to be known about the underlying mechanisms and determinants of genomic diversity. Carcinogenesis is a dynamic,...

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PMID: 26578615
DOI: 10.1200/jco.2015.62.0096

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