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Article

Targeted multi-layer analysis of PANoptosis-associated genes in the etiology of chronic kidney disease.

Human genomics - 13 May 2025

Li Tong, Zhang Yingyue, Wang Xingzhi, Liu Qi, Ma Xiaofei, Sui Manshu

Abstract excerpt

BACKGROUND: Previous studies have examined the cellular and molecular interactions between chronic kidney disease (CKD) and PANoptosis, yet the genetic underpinnings remain unclear. MATERIALS: Data at the summary level regarding the methylation, gene expression, and protein levels associated with PANoptosis were obtained from quantitative trait locus (QTL) studies. Genome-wide association study (GWAS) summary...

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Topics

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Share to DNA Methylation
Share to MADD gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Hepatocyte Growth Factor

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Renal Insufficiency, Chronic

Source

Open in PubMed Open full text

Identifiers

PMID: 40361162
DOI: 10.1186/s40246-025-00768-z
PMCID: PMC12077045

Genes

CCND1
HGF
MADD
GUCY2D

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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