Article
DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney disease
19 Nov 2013
Abstract excerpt
Genetic risk factors for chronic kidney disease (CKD) are being identified through international collaborations. By comparison, epigenetic risk factors for CKD have only recently been considered using population-based approaches. DNA methylation is a major epigenetic modification that is associated with complex diseases, so we investigated methylome-wide loci for association with CKD. A total of 485,577 unique...
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