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Thalamocortical connectivity and its relationship with symptoms and cognition across the psychosis continuum.

Psychological medicine - 1 Sept 2023

Ramsay Ian S, Mueller Bryon, Ma Yizhou, Shen Chen, Sponheim Scott R

Abstract excerpt

BACKGROUND: Coordination between the thalamus and cortex is necessary for efficient processing of sensory information and appears disrupted in schizophrenia. The significance of this disrupted coordination (i.e. thalamocortical dysconnectivity) to the symptoms and cognitive deficits of schizophrenia is unclear. It is also unknown whether similar dysconnectivity is observed in other forms of psychotic...

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PMID: 36047043
DOI: 10.1017/S0033291722002793

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