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Article

HLA Polymorphisms Linked to the Severity and Extent of Periodontitis in Patients with Type 1 Diabetes from a Brazilian Mixed Population.

International journal of environmental research and public health - 27 Mar 2025

Menezes Carlos Felipe Sousa, Lage Lucas Meneses, Santos Luís Gustavo Souza, Nascimento Gilvan Cortês, Magalhães Marcelo, Facundo Alexandre, Silva Dayse Aparecida, Porto Luís Cristóvão, Gomes Marília Brito, Faria Manuel Dos Santos, Azulay Rossana Sousa, Rodrigues Vandilson

Abstract excerpt

This study aimed to investigate the relationship between Class II human leukocyte antigen (HLA) alleles (DRB1, DQA1, and DQB1) and the severity and extent of periodontitis in patients with Type 1 diabetes (T1D). A cross-sectional study was conducted with 49 patients with T1D. Demographic data and diabetes history were collected. A clinical examination was performed to assess periodontal variables. The patients...

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Identifiers

PMID: 40283738
DOI: 10.3390/ijerph22040512
PMCID: PMC12026859

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