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Polymorphisms in risk genes of type 2 diabetes mellitus could be also markers of susceptibility to periodontitis.

Archives of oral biology - 1 Nov 2022

Silva Arles Naisa Amaral, Nicchio Ingra Gagno, da Silva Bárbara Roque, Martelli Maurício Gandini Giani, Hidalgo Marco A Rimachi, Nepomuceno Rafael, Theodoro Letícia H, Cirelli Joni A, Orrico Silvana R P, Cirelli Thamiris, Barros Silvana P, Scarel-Caminaga Raquel M

Abstract excerpt

OBJECTIVES: This study aimed to investigate polymorphisms in genes considered molecular biomarkers of type 2 diabetes mellitus (T2DM) to assess whether they are associated with periodontitis, and relating them to the periodontal status, glycemic and lipid profile of the subjects. DESIGN: We investigated individuals who underwent complete periodontal examination and biochemical evaluation. We categorized them into...

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PMID: 36058090
DOI: 10.1016/j.archoralbio.2022.105529

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